McCarthy, who is also chairman of department store retailer House of Fraser and jewellery group Aurum, joined the board of the beleaguered menswear retailer in May 2007 when Baugur held a 28.5 per cent stake in the business.
His departure follows the collapse of a£40 million takeover bid for Moss Bros by Icelandic investor Baugur earlier this year.
In a stock exchange announcement today Moss Bros said: “The board expresses their gratitude to him for his help and support to the company.”
Earlier this month, Moss Bros issued a profit warning after like-for-likes slumped 3.6 per cent in the 44 weeks to the end of November.
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