Accountancy firm Vantis has been appointed to handle the administration. It is not currently seeking a buyer for the business.
Miss Sixty has 11 UK stores and concessions which are all continuing to trade.
This is latest in a growing list of retailers filing for administration as trading continues to free fall on the back of the credit crunch and falling consumer confidence.
Hardy Amies, Rosebys and fashion and homewares retailer Joy have also collapsed in the last week.
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